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Review
. 2010 Apr;48(4):1019-25.
doi: 10.1128/JCM.00219-10. Epub 2010 Feb 24.

Extended-spectrum-beta-lactamase, AmpC, and Carbapenemase issues

Kenneth S Thomson  1
Affiliations
Review

Extended-spectrum-beta-lactamase, AmpC, and Carbapenemase issues

Kenneth S Thomson. J Clin Microbiol. 2010 Apr.
No abstract available

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Figures

FIG. 1.
FIG. 1.
E. coli that produces an ESBL and a high level of AmpC. Shown is a CLSI ESBL confirmatory test on Mueller-Hinton agar supplemented with 200 μg/ml cloxacillin. No inhibition zones were obtained on unsupplemented Mueller-Hinton agar. The disks, from left to right, are as follows: upper, ceftazidime-clavulanate and ceftazidime; lower, cefotaxime-clavulanate and cefotaxime.
FIG. 2.
FIG. 2.
AmpC disk test with the upper Tris/EDTA disk inoculated with the test isolate according to the method of Black et al. (4) and placed adjacent to a cefoxitin (FOX) disk on a lawn of cefoxitin-susceptible E. coli. The indented zone margin is evidence of hydrolysis of cefoxitin by the AmpC enzymes that diffused out of the permeabilized cells on the Tris/EDTA disk.
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References

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