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Comparative Study
. 2010 Apr;48(4):1458-60.
doi: 10.1128/JCM.02311-09. Epub 2010 Feb 24.

Human papillomavirus genotyping using archival vulval dysplastic or neoplastic biopsy tissues: comparison between the INNO-LiPA and linear array assays

Sarah E Tan  1 , Suzanne M Garland, Alice R Rumbold, Sepehr N Tabrizi
Affiliations
Comparative Study

Human papillomavirus genotyping using archival vulval dysplastic or neoplastic biopsy tissues: comparison between the INNO-LiPA and linear array assays

Sarah E Tan et al. J Clin Microbiol. 2010 Apr.

Abstract

The Roche Linear Array (LA) and Innogenetics INNO-LiPA human papillomavirus (HPV) genotyping assays were compared for paraffin-embedded vulval tissues. The LA detected amplifiable DNA in 28 (57%) out of 49 biopsy specimens, 20 (40%) being HPV genotyped, compared to 49 (100%) and 41 (83%), respectively, detected by the INNO-LiPA. The INNO-LiPA provides greater sensitivity for HPV genotyping in archival tissue.

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