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Review
. 2009 May;28(5):586-600.
doi: 10.1080/15257770903054159.

The unabated synthesis of new nucleoside analogues with antiviral potential: a tribute to Morris J. Robins

Erik De Clercq  1
Affiliations
Review

The unabated synthesis of new nucleoside analogues with antiviral potential: a tribute to Morris J. Robins

Erik De Clercq. Nucleosides Nucleotides Nucleic Acids. 2009 May.

Abstract

The furo[2,3-d]pyrimidin-2(3H)-one is the key structural determinant in the exquisitely potent activity of its derivatives (R = 2-deoxyribosyl; R' = p-pentylphenyl) against VZV (varicella-zoster virus) replication. [structure: see text].

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