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Review
. 2010;220(3):234-7.
doi: 10.1159/000275676. Epub 2010 Feb 20.

Cutaneous sarcoidosis occurring during anti-TNF-alpha treatment: report of two cases

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Review

Cutaneous sarcoidosis occurring during anti-TNF-alpha treatment: report of two cases

F Dhaille et al. Dermatology. 2010.

Abstract

We report two cases of cutaneous granuloma induced by anti-TNF-alpha therapy: a 47-year-old man suffering from psoriatic arthritis treated with infliximab and a 56-year-old woman treated with adalimumab for polyarticular juvenile rheumatoid arthritis. The biospies confirmed the diagnosis of a 'sarcoidosis-like' reaction. No systemic involvement was observed. Such cases of noninfectious granulomatous diseases occurring during anti-TNF-alpha therapy are becoming increasingly frequent.

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