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Comment
. 2010 Mar;77(6):487-9.
doi: 10.1038/ki.2009.544.

Better nephrology for mice--and man

Matthew D Breyer  1 , Zhonghua Qi
Affiliations
Free article
Comment

Better nephrology for mice--and man

Matthew D Breyer et al. Kidney Int. 2010 Mar.
Free article

Abstract

The use of creatinine to estimate glomerular filtration rate in patients is prone to well-described artifacts that impact its interpretation. Eisner et al. now show that the impact of creatinine secretion on creatinine clearance is even larger in mice than in humans, raising questions regarding the utility of creatinine for measuring glomerular filtration rate in mice.

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