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. 2010 Feb 18:4:73-6.
doi: 10.2147/opth.s8599.

Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

Ip Theocharis  1
Affiliations

Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

Ip Theocharis. Clin Ophthalmol. .

Abstract

Purpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).

Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;

Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded.

Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.

Keywords: fibrinogen; pathogenesis; retinal detachment.

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Figures

Figure 1
Figure 1
Fibrinogen and extension of the detachment (scatter plot). Notes: Each point represents one retinal detachment case. Abbreviation: FPL, fibrinogen plasma levels.
See this image and copyright information in PMC

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