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. 2010 Feb;33(2):72-6.
doi: 10.1002/clc.20692.

Correlation study of pulmonary embolism and high-density lipoprotein cholesterol

YuPeng Wang  1 , Ping Wang, HongWei Li
Affiliations

Correlation study of pulmonary embolism and high-density lipoprotein cholesterol

YuPeng Wang et al. Clin Cardiol. 2010 Feb.

Abstract

Background: It is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high-density lipoprotein cholesterol.

Hypothesis: Pulmonary embolism has a negative correlation with the level of high-density lipoprotein cholesterol.

Methods: A total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non-trunk embolism in group B.

Results: The results showed that the level of high-density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non-trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high-density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C-reactive protein.

Conclusions: Pulmonary arterial trunk embolism is negatively correlated with the level of high-density lipoprotein cholesterol.

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