Visualizing PKA dynamics in a learning center
- PMID: 20188649
- DOI: 10.1016/j.neuron.2010.02.009
Visualizing PKA dynamics in a learning center
Abstract
Gervasi et al. report in this issue of Neuron that the mushroom bodies in Drosophila, a critical center for olfactory memory formation, have spatially restricted PKA activity in response to specific neuromodulators. The dunce cAMP-phosphodiesterase and rutabaga adenylyl cyclase genes are necessary for two key properties of PKA dynamics in these neurons.
Comment on
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PKA dynamics in a Drosophila learning center: coincidence detection by rutabaga adenylyl cyclase and spatial regulation by dunce phosphodiesterase.Neuron. 2010 Feb 25;65(4):516-29. doi: 10.1016/j.neuron.2010.01.014. Neuron. 2010. PMID: 20188656
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