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Comment
. 2010 Feb 26;32(2):141-2.
doi: 10.1016/j.immuni.2010.02.005.

For T cell receptors, some breakups might not last forever

Christopher C Govern  1 , Arup K Chakraborty
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For T cell receptors, some breakups might not last forever

Christopher C Govern et al. Immunity. .
Free article

Abstract

Does the affinity or half-life of peptide-MHC-T cell receptor (TCR) interactions determine T cell activation? In this issue of Immunity, Aleksic et al. (2010) propose a role for the on rate through multiple rebindings to the same TCR.

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