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Comment
. 2010 Apr;9(4):333-5.
doi: 10.1016/S1474-4422(10)70055-7. Epub 2010 Feb 26.

Testing the amyloid hypothesis of Alzheimer's disease in vivo

Sam Gandy
Comment

Testing the amyloid hypothesis of Alzheimer's disease in vivo

Sam Gandy. Lancet Neurol. 2010 Apr.
No abstract available

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Figures

Figure
Figure
Cerebral amyloid plaque visualized with luminescent oligothiophenes. Each color represents a discrete misfolding state of Aβ (Image courtesy of Patrick Hof, Dara Dickstein, Peter Nilsson, and Sam Gandy) (Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, Aguzzi A, Hammarström P, Nilsson KP. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. ACS Chem Biol. 2009 Aug 21;4(8):673–84. PubMed PMID: 19624097)
See this image and copyright information in PMC

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