Role of neuropathy on fracture healing in Charcot neuro-osteoarthropathy
- PMID: 20190384
Role of neuropathy on fracture healing in Charcot neuro-osteoarthropathy
Abstract
Charcot neuro-osteoarthropathy (CNO) is a devastating condition affecting most commonly the foot/ankle joint in diabetic patients and may lead to severe deformities and amputation. Peripheral sensory neuropathy seems to be a pre-requisite to the development of CNO. The aim of this review article is to summarise the skeletal effects of the nervous system on bone remodelling and fracture healing of normal and damaged joints and to describe how neuropathy, in the context of modern concept of neuro-osteopathology, is crucial in the predisposition of the patient to develop acute CNO.
Comment in
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About the role of neuropathy on fracture healing in charcot neuro-osteoarthropathy.J Musculoskelet Neuronal Interact. 2010 Jun;10(2):188; author reply 189-90. J Musculoskelet Neuronal Interact. 2010. PMID: 20516637 No abstract available.
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