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Review
. 2010 Apr;8(4):251-9.
doi: 10.1038/nrmicro2312. Epub 2010 Mar 1.

Call of the wild: antibiotic resistance genes in natural environments

Heather K Allen  1 , Justin Donato, Helena Huimi Wang, Karen A Cloud-Hansen, Julian Davies, Jo Handelsman
Affiliations
Review

Call of the wild: antibiotic resistance genes in natural environments

Heather K Allen et al. Nat Rev Microbiol. 2010 Apr.

Abstract

Antibiotic-resistant pathogens are profoundly important to human health, but the environmental reservoirs of resistance determinants are poorly understood. The origins of antibiotic resistance in the environment is relevant to human health because of the increasing importance of zoonotic diseases as well as the need for predicting emerging resistant pathogens. This Review explores the presence and spread of antibiotic resistance in non-agricultural, non-clinical environments and demonstrates the need for more intensive investigation on this subject.

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