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Comment
. 2010 Mar;12(3):207-9.
doi: 10.1038/ncb0310-207.

p62, an autophagy hero or culprit?

Tor Erik Rusten  1 , Harald Stenmark
Affiliations
Comment

p62, an autophagy hero or culprit?

Tor Erik Rusten et al. Nat Cell Biol. 2010 Mar.

Abstract

The p62 protein recognizes toxic cellular waste, which is then scavenged by a sequestration process known as self-eating or autophagy. Lack of autophagy leads to accumulation of p62, which is not good for liver cells, as it induces a cellular stress response that leads to disease.

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References

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