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Editorial
. 2010 Apr;55(4):844-5.
doi: 10.1161/HYPERTENSIONAHA.109.148932. Epub 2010 Mar 1.

Obesity, sympathetic overdrive, and hypertension: the leptin connection

Kamal Rahmouni
Editorial

Obesity, sympathetic overdrive, and hypertension: the leptin connection

Kamal Rahmouni. Hypertension. 2010 Apr.
No abstract available

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Conflict of interest statement

Disclosure None.

Figures

Figure
Figure
Selective leptin resistance help explain how high levels of circulating leptin in obesity may contribute to hypertension and sympathetic overdrive despite resistance to metabolic effects of this hormone. Long-term renal sympathetic stimulation caused by high leptin levels could raise renal sympathetic tone leading to hypertension while loss of leptin's ability to decrease food intake and increase thermogenesis promote obesity by increasing adiposity.
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Comment on

References

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