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Review
. 2010 Mar;7(3 Suppl):S16-25.
doi: 10.1038/nmeth.1434.

Visualization of multiple alignments, phylogenies and gene family evolution

James B Procter  1 , Julie Thompson, Ivica Letunic, Chris Creevey, Fabrice Jossinet, Geoffrey J Barton
Affiliations
Review

Visualization of multiple alignments, phylogenies and gene family evolution

James B Procter et al. Nat Methods. 2010 Mar.

Abstract

Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.

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References

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