Review
doi: 10.1677/JME-09-0143.
Epub 2010 Mar 3.
Adrenocortical development and cancer: focus on SF-1
Affiliations
- PMID: 20200142
- DOI: 10.1677/JME-09-0143
Item in Clipboard
Review
Adrenocortical development and cancer: focus on SF-1
J Mol Endocrinol.
2010 Jun.
Abstract
Steroidogenic factor-1 (SF-1/Ad4-binding protein; NR5A1) is an essential regulator of tissue-specific gene expression in steroidogenic cells and of adrenogonadal development. Here, I discuss recent data in the literature showing the implication of SF-1 and the importance of its dosage not only during development but also for adrenal cortex tumorigenesis in humans and mice.
Similar articles
-
Molecular aspects of steroidogenic factor 1 (SF-1).Mol Cell Endocrinol. 2010 Feb 5;315(1-2):27-39. doi: 10.1016/j.mce.2009.07.003. Epub 2009 Jul 16. Mol Cell Endocrinol. 2010. PMID: 19616058 Review.
-
Differential gene dosage effects of Ad4BP/SF-1 on target tissue development.Biochem Biophys Res Commun. 2006 Mar 24;341(4):1036-45. doi: 10.1016/j.bbrc.2006.01.058. Epub 2006 Jan 25. Biochem Biophys Res Commun. 2006. PMID: 16458255
-
Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis.Endocrinology. 2007 Feb;148(2):693-704. doi: 10.1210/en.2006-0681. Epub 2006 Nov 2. Endocrinology. 2007. PMID: 17082260
-
SF-1 overexpression in childhood adrenocortical tumours.Eur J Cancer. 2006 May;42(8):1040-3. doi: 10.1016/j.ejca.2006.01.022. Epub 2006 Mar 29. Eur J Cancer. 2006. PMID: 16574405
-
[An ambiguous role of steroidogenic factor 1 in the rat GnRH receptor gene expression. Lessons from transgenic mice].J Soc Biol. 2004;198(1):73-9. J Soc Biol. 2004. PMID: 15146959 Review. French.
Cited by
-
[Tumors of the adrenal glands : Update].Pathologe. 2019 Jul;40(4):467-492. doi: 10.1007/s00292-019-0618-z. Pathologe. 2019. PMID: 31250089 German.
-
Adrenocortical carcinoma - towards genomics guided clinical care.Nat Rev Endocrinol. 2019 Sep;15(9):548-560. doi: 10.1038/s41574-019-0221-7. Nat Rev Endocrinol. 2019. PMID: 31147626 Review.
-
Comprehensive Characterization of the Regulatory Landscape of Adrenocortical Carcinoma: Novel Transcription Factors and Targets Associated with Prognosis.Cancers (Basel). 2022 Oct 27;14(21):5279. doi: 10.3390/cancers14215279. Cancers (Basel). 2022. PMID: 36358698 Free PMC article.
-
Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells.PLoS One. 2012;7(3):e32080. doi: 10.1371/journal.pone.0032080. Epub 2012 Mar 9. PLoS One. 2012. PMID: 22427816 Free PMC article.
-
FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria.EMBO Rep. 2016 Sep;17(9):1264-80. doi: 10.15252/embr.201541504. Epub 2016 Jul 11. EMBO Rep. 2016. PMID: 27402544 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
