Treating silent reflux disease does not improve poorly controlled asthma
- PMID: 20200165
- DOI: 10.3949/ccjm.77a.09111
Treating silent reflux disease does not improve poorly controlled asthma
Abstract
Many patients with asthma also have gastroesophageal reflux disease (GERD), and GERD can cause symptoms that mimic those of poorly controlled asthma. Patients with poorly controlled asthma are often treated empirically for GERD, whether or not they have symptomatic reflux. However, a randomized, placebo-controlled trial funded by the American Lung Association and the National Institutes of Health found that treating silent GERD does not improve asthma control. These results warrant a reevaluation of current guidelines and clinical practice.
Similar articles
-
Gastroesophageal reflux disease and asthma.Curr Opin Pulm Med. 2010 Jan;16(1):60-3. doi: 10.1097/MCP.0b013e328332ca2f. Curr Opin Pulm Med. 2010. PMID: 19887939 Review.
-
[Retrospective analysis of coexistence of acidic gastroesophageal reflux in children with atopic bronchial asthma].Przegl Lek. 2007;64 Suppl 3:115-7. Przegl Lek. 2007. PMID: 18431932 Polish.
-
Prolonged ambulatory pH monitoring in patients with persistent gastroesophageal reflux disease symptoms: testing while on therapy identifies the need for more aggressive anti-reflux therapy.Am J Gastroenterol. 1996 Oct;91(10):2110-3. Am J Gastroenterol. 1996. PMID: 8855731
-
Bronchial hyperreactivity in non-atopic children with asthma and reflux: effect of anti-reflux treatment.Pediatr Pulmonol. 2009 Nov;44(11):1070-4. doi: 10.1002/ppul.21094. Pediatr Pulmonol. 2009. PMID: 19830719
-
Effectiveness and safety of proton pump inhibitors in infantile gastroesophageal reflux disease.Ann Pharmacother. 2010 Mar;44(3):572-6. doi: 10.1345/aph.1M519. Epub 2010 Feb 2. Ann Pharmacother. 2010. PMID: 20124466 Review.
Cited by
-
Management of comorbidities in difficult and severe asthma.Breathe (Sheff). 2023 Sep;19(3):230133. doi: 10.1183/20734735.0133-2023. Epub 2023 Nov 14. Breathe (Sheff). 2023. PMID: 38020342 Free PMC article. Review.
-
Pharmacological and surgical interventions for the treatment of gastro-oesophageal reflux in adults and children with asthma.Cochrane Database Syst Rev. 2021 May 17;5(5):CD001496. doi: 10.1002/14651858.CD001496.pub2. Cochrane Database Syst Rev. 2021. PMID: 33998673 Free PMC article.
-
Is There a Relationship Between GERD and Asthma?Gastroenterol Hepatol (N Y). 2012 Jun;8(6):401-3. Gastroenterol Hepatol (N Y). 2012. PMID: 22933878 Free PMC article. No abstract available.
-
Patient-centered care and its effect on outcomes in the treatment of asthma.Patient Relat Outcome Meas. 2011 Jul;2:81-109. doi: 10.2147/PROM.S12634. Epub 2011 Mar 6. Patient Relat Outcome Meas. 2011. PMID: 22915970 Free PMC article.
-
Gastroesophageal reflux disease and pulmonary function: a potential role of the dead space extension.Med Sci Monit. 2012 May;18(5):CR271-5. doi: 10.12659/msm.882731. Med Sci Monit. 2012. PMID: 22534705 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical