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. 1991 Jan 2;121(1-2):191-3.
doi: 10.1016/0304-3940(91)90682-j.

A muscarine-activated voltage-independent K+ channel in cultured bullfrog sympathetic neurones

K Tanaka  1 , K Koyano, K Kuba
Affiliations

A muscarine-activated voltage-independent K+ channel in cultured bullfrog sympathetic neurones

K Tanaka et al. Neurosci Lett. .

Abstract

In cultured bullfrog sympathetic neurones, cell-attached patch clamp revealed a voltage-independent K+ channel having a conductance of 46-113 pS at an external K+ of 2-120 mM. Muscarine (10-20 microM), applied to the cell membrane outside a recording pipette, increased its open probability and mean open time in an atropine-sensitive manner. This muscarine-activated K+ channel could underlie some of the muscarinic inhibitory postsynaptic potentials in both central and peripheral nervous systems.

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