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. 2010 Feb 3:3:49.
doi: 10.1186/1757-1626-3-49.

A male presenting with a primary mucinous bladder carcinoma: a case report

Konstantinos Sigalas  1 , Stavros I Tyritzis, Eleni Trigka, Ioannis Katafigiotis, Nikolaos Kavantzas, Konstantinos G Stravodimos
Affiliations

A male presenting with a primary mucinous bladder carcinoma: a case report

Konstantinos Sigalas et al. Cases J. .

Abstract

Background: The primary mucinous adenocarcinoma of the bladder is an extremely rare urologic entity, which is found in less than 2% of all urinary bladder tumours and is often presented as metastatic.

Case presentation: A 69-year old male patient was diagnosed with a primary mucinous adenocarcinoma of the bladder after undergoing a transurethral resection of a bladder tumour and complete examination of the entire gastrointestinal tract to rule out other primary cites. Immunohistochemistry confirmed the nature of the tumour. The patient underwent a radical cystoprostatectomy with en block bilateral pelvic lymphadenectomy and urinary diversion with a Bricker ileostomy.

Conclusion: The primary adenocarcinoma creates a diagnostic dilemma, since it cannot be easily differentiated by the adenocarcinoma that originates from the colon and the prostate. We advocate the radical surgical management, after exclusion of any primary malignant sites related to the gastrointestinal tract. The immunohistochemistry has a leading role, assisting with the differential diagnosis.

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Figures

Figure 1
Figure 1
a, Intravenous urogram showing a radiolucent filling defect in the bladder and a non functioning left kidney and b, computed tomography of the pelvis.
Figure 2
Figure 2
a, Pools of extracellular mucin containing glandular configurations, b, signet-ring cells.
Figure 3
Figure 3
a, Intracellular and extracellular mucin PAS-d positive, b, glandular configurations CK7 positive and c, signet-ring cells CK20 positive.
See this image and copyright information in PMC

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