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Editorial
. 2010 Mar;95(3):348-51.
doi: 10.3324/haematol.2009.019141.

Pathophysiology and treatment of the myelodysplastic syndrome with isolated 5q deletion

Martin Jädersten
Editorial

Pathophysiology and treatment of the myelodysplastic syndrome with isolated 5q deletion

Martin Jädersten. Haematologica. 2010 Mar.
No abstract available

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Figures

Figure 1.
Figure 1.
Overview of the pathophysiology of the 5q- syndrome.
See this image and copyright information in PMC

References

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    1. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2008.
    1. Nilsson L, Astrand-Grundstrom I, Arvidsson I, Jacobsson B, Hellstrom-Lindberg E, Hast R, et al. Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level. Blood. 2000;96(6):2012–21. - PubMed
    1. Jaju RJ, Jones M, Boultwood J, Kelly S, Mason DY, Wainscoat JS, et al. Combined immunophenotyping and FISH identifies the involvement of B-cells in 5q- syndrome. Genes Chromosomes Cancer. 2000;29(3):276–80. - PubMed
    1. Kiladjian JJ, Bourgeois E, Lobe I, Braun T, Visentin G, Bourhis JH, et al. Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes. Leukemia. 2006;20(3):463–70. - PubMed

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