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Review
. 2010 Jun;24(5):404-12.
doi: 10.1177/1545968309354536. Epub 2010 Mar 5.

The mirror neuron system: a neural substrate for methods in stroke rehabilitation

Affiliations
Review

The mirror neuron system: a neural substrate for methods in stroke rehabilitation

Kathleen A Garrison et al. Neurorehabil Neural Repair. 2010 Jun.

Abstract

Mirror neurons found in the premotor and parietal cortex respond not only during action execution, but also during observation of actions being performed by others. Thus, the motor system may be activated without overt movement. Rehabilitation of motor function after stroke is often challenging due to severity of impairment and poor to absent voluntary movement ability. Methods in stroke rehabilitation based on the mirror neuron system--action observation, motor imagery, and imitation--take advantage of this opportunity to rebuild motor function despite impairments, as an alternative or complement to physical therapy. Here the authors review research into each condition of practice, and discuss the relevance of the mirror neuron system to stroke recovery.

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Conflict of interest statement

Declaration of Conflicting Interests

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1.
Figure 1.
The core mirror neuron system, including the inferior parietal lobule (IPL), ventral premotor cortex (PMv), and inferior frontal gyrus (IFG).

References

    1. National Institute of Neurological Disorders and Stroke. Report of the stroke progress review group: September 2006. http://www.ninds.nih.gov/find_people/groups/stroke_prg/09_2006_stroke_pr.... Updated June 5, 2009. Accessed October 27, 2009.
    1. Mayo NE, Wood-Dauphinee S, Cote R, Durcan L, Carlton J. Activity, participation, and quality of life 6 months poststroke. Arch Phys Med Rehabil. 2002;83:1035–1042. - PubMed
    1. Winstein CJ, Wolf SL. Task-oriented training to promote upper extremity recovery. In: Stein J, Harvey R, Macko R, Winstein CJ, Zorowitz R, eds. Stroke Recovery and Rehabilitation. New York, NY: Demos Medical Publishing; 2008.
    1. Nudo RJ. Mechanisms for recovery of motor function following cortical damage. Curr Opin Neurobiol. 2006;16: 638–644. - PubMed
    1. Rizzolatti G The mirror neuron system and its function in humans. Anat Embryol (Berl). 2005;210:419–421. - PubMed