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. 2010 Mar;82(3):508-11.
doi: 10.4269/ajtmh.2010.09-0322.

Chikungunya virus in North-Eastern Italy: a seroprevalence survey

Maria Luisa Moro  1 , Carlo Gagliotti, Giuliano Silvi, Raffaella Angelini, Vittorio Sambri, Giovanni Rezza, Erika Massimiliani, Andrea Mattivi, Elisa Grilli, Alba Carola Finarelli, Nadir Spataro, Anna Maria Pierro, Thomas Seyler, Pierluigi Macini; Chikungunya Study Group
Affiliations

Chikungunya virus in North-Eastern Italy: a seroprevalence survey

Maria Luisa Moro et al. Am J Trop Med Hyg. 2010 Mar.

Abstract

After an outbreak of Chikungunya infection in Emilia-Romagna Region (North-eastern Italy), a survey was performed to estimate the seroprevalence of antibody to Chikungunya virus and the proportion of asymptomatic infections, to identify factors associated with infection, and evaluate the performance of the surveillance system. The method used was a survey on a random sample of residents of the village with the largest number of reported cases. The prevalence was 10.2% (33 of 325), being higher in older people and males, and lower when window screens and insect repellents were used. Only 18% of infected persons were fully asymptomatic, 85% of the 27 symptomatic confirmed cases satisfied the surveillance case definition, and 63% of the persons meeting the criteria for suspect case were identified by the active surveillance system. This study provides basic parameters for modeling the transmission potential of outbreaks and planning control measures for Chikungunya infection in temperate settings.

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