Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010;74(3):663-6.
doi: 10.1271/bbb.90764. Epub 2010 Mar 7.

Pro-oxidant action of pyrroloquinoline quinone: characterization of protein oxidative modifications

Takeshi Ishii  1 , Mitsugu Akagawa, Yuji Naito, Osamu Handa, Tomohisa Takagi, Taiki Mori, Shigenori Kumazawa, Toshikazu Yoshikawa, Tsutomu Nakayama
Affiliations
Free article

Pro-oxidant action of pyrroloquinoline quinone: characterization of protein oxidative modifications

Takeshi Ishii et al. Biosci Biotechnol Biochem. 2010.
Free article

Abstract

Pyrroloquinoline quinone (PQQ), a putative essential nutrient, is a redox modulator in cell and animal models. Here we characterized PQQ-induced protein oxidative modifications in a model peptide and protein, and we propose that the mechanism of protein modification by PQQ is redox cycling-mediated oxidation. PQQ may contribute to the regulation of intracellular protein functions through its prooxidant action.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles