Treatment and Prevention of Neonatal Anemia
- PMID: 20209037
- PMCID: PMC2832331
- DOI: 10.1542/neo.9-11-e526
Treatment and Prevention of Neonatal Anemia
Abstract
Because red blood cell (RBC) transfusion therapy remains the primary treatment of anemia encountered in early life, the basis for RBC transfusion in the treatment of symptomatic anemia is discussed in this review along with several important aspects of neonatal blood banking practices. Nontransfusion approaches to the prevention and treatment of neonatal anemia also are described. Finally, this review covers the controversy surrounding whether neonatal RBC transfusion therapy should be restrictive or liberal. The evaluation and treatment of uncommon and rare acquired and genetic causes of anemia in newborn infants are beyond the scope of this review.
References
-
- Stockman JA, III, Garcia JF, Oski FA. The anemia of prematurity: factors governing the erythropoietin response. N Engl J Med. 1977;296:647–650. - PubMed
-
- Kirpalani H, Whyte RK, Andersen C, et al. The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants. J Pediatr. 2006;149:301–307. - PubMed
-
- Widness JA, Seward VJ, Kromer IJ, Burmeister LF, Bell EF, Strauss RG. Changing patterns of red blood cell transfusion in very low birth weight infants. J Pediatr. 1996;129:680–687. - PubMed
Grants and funding
LinkOut - more resources
Full Text Sources
