Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Nov;87(11):782-5.

Incidence of mucopolysaccharidoses in Tunisia

Hadhami Ben Turkia  1 , Néji Tebib, Hatem Azzouz, Mohamed S Abdelmoula, Amal Ben Chehida, Jalel Chemli, Kamel Monastiri, Malak Chaabouni, Haifa Sanhagi, Béchir Zouari, Naziha Kaabachi, Marie F Ben Dridi
Affiliations
  • PMID: 20209839
Free article

Incidence of mucopolysaccharidoses in Tunisia

Hadhami Ben Turkia et al. Tunis Med. 2009 Nov.
Free article

Abstract

Background: The mucopolysaccharidoses (MPS) are a devastating heterogenous group of lysosomal storage disorders.

Aim: To evaluate the epidemiological profile of MPS in Tunisia.

Methods: we conducted a retrospective epidemiological survey covering the period 1970-2005. Multiple sources were used to identify affected patients.

Results: Ninety six confirmed MPS cases were collected from 132 suspected cases found in the surveyed data. Of the ninety six confirmed cases, 20% were from multiplex families. Consanguinity was found in 83% of the families. The crude rate for all types of mucopolysaccharidoses was 2.3 cases in 100,000 live births. The prevalence of MPS type I, III and IV, those most frequently occurring in the collected data, were estimated at 0.63, 0.7 and 0.45 per 100,000 live births, respectively. The cumulative incidence of MPS type VI (0.3 per 105 live births) was higher than reported in European countries; but, it is likely that...

Conclusion: The reported frequency of all types of MPS in Tunisia is underestimated.

PubMed Disclaimer

LinkOut - more resources