Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010;11(2):103.
doi: 10.1186/gb-2010-11-2-103. Epub 2010 Feb 16.

Filling the gaps in the genomic landscape

David Williams  1 , J Peter Gogarten, Pascal Lapierre
Affiliations
Comment

Filling the gaps in the genomic landscape

David Williams et al. Genome Biol. 2010.

Abstract

A new initiative provides comparative genomicists with a more complete picture of genome diversity. Here we discuss the improved sampling strategy.

PubMed Disclaimer

Comment on

  • A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea.
    Wu D, Hugenholtz P, Mavromatis K, Pukall R, Dalin E, Ivanova NN, Kunin V, Goodwin L, Wu M, Tindall BJ, Hooper SD, Pati A, Lykidis A, Spring S, Anderson IJ, D'haeseleer P, Zemla A, Singer M, Lapidus A, Nolan M, Copeland A, Han C, Chen F, Cheng JF, Lucas S, Kerfeld C, Lang E, Gronow S, Chain P, Bruce D, Rubin EM, Kyrpides NC, Klenk HP, Eisen JA. Wu D, et al. Nature. 2009 Dec 24;462(7276):1056-60. doi: 10.1038/nature08656. Nature. 2009. PMID: 20033048 Free PMC article.

References

    1. Wu D, Hugenholtz P, Mavromatis K, Pukall R, Dalin E, Ivanova N, Kunin V, Goodwin L, Wu M, Tindall B, Hooper S, Pati A, Lykidis A, Spring S, Anderson I, Dhaeseleer P, Zemla A, Singer M, Lapidus A, Nolan M, Copeland A, Han C, Chen F, Cheng JF, Lucas S, Kerfeld C, Lang E, Gronow S, Chain P, Bruce D. et al.A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea. Nature. 2009;462:1056–1060. doi: 10.1038/nature08656. - DOI - PMC - PubMed
    1. Welch R, Burland V, PlunkettIII G, Redford P, Roesch P, Rasko D, Buckles E, Liou SR, Boutin A, Hackett J, Stroud D, Mayhew G, Rose D, Zhou S, Schwartz D, Perna N, Mobley H, Donnenberg M, Blattner F. Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli. Proc Natl Acad Sci USA. 2002;99:17020–17024. doi: 10.1073/pnas.252529799. - DOI - PMC - PubMed
    1. Normand P, Lapierre P, Tisa L, Gogarten J, Alloisio N, Bagnarol E, Bassi C, Berry A, Bickhart D, Choisne N, Couloux A, Cournoyer B, Cruveiller S, Daubin V, Demange N, Francino M, Goltsman E, Huang Y, Kopp O, Labarre L, Lapidus A, Lavire C, Marechal J, Martinez M, Mastronunzio J, Mullin B, Niemann J, Pujic P, Rawnsley T, Rouy Z. et al.Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography. Genome Res. 2007;17:7–15. doi: 10.1101/gr.5798407. - DOI - PMC - PubMed
    1. Tettelin H, Masignani V, Cieslewicz M, Donati C, Medini D, Ward N, Angiuoli S, Crabtree J, Jones A, Durkin A, DeBoy R, Davidsen T, Mora M, Scarselli M, Margarit Y, Ros I, Peterson J, Hauser C, Sundaram J, Nelson W, Madupu R, Brinkac L, Dodson R, Rosovitz M, Sullivan S, Daugherty S, Haft D, Selengut J, Gwinn M, Zhou L. et al.Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial "pan-genome". Proc Natl Acad Sci USA. 2005;102:13950–13955. doi: 10.1073/pnas.0506758102. - DOI - PMC - PubMed
    1. Lapierre P, Gogarten J. Estimating the size of the bacterial pan-genome. Trends Genet. 2009;25:107–110. doi: 10.1016/j.tig.2008.12.004. - DOI - PubMed

LinkOut - more resources