doi: 10.1016/j.cell.2010.02.017.
Membrane curvature in synaptic vesicle fusion and beyond
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- PMID: 20211126
- DOI: 10.1016/j.cell.2010.02.017
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Membrane curvature in synaptic vesicle fusion and beyond
Cell.
.
Free article
Abstract
Recent evidence suggests that the Ca(2+)-sensors synaptotagmin-1 and Doc2b deform synaptic membranes during synaptic vesicle exocytosis. We discuss how local curvature generated by these and other proteins may stimulate membrane fusion and discuss the potential implications of these findings for other cellular fusion events.
(c) 2010 Elsevier Inc. All rights reserved.
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