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Review
. 2010 Mar;67(6):841-60.
doi: 10.1007/s00018-009-0193-1.

Biological activity of phenolic lipids

Maria Stasiuk  1 , A Kozubek
Affiliations
Review

Biological activity of phenolic lipids

Maria Stasiuk et al. Cell Mol Life Sci. 2010 Mar.

Abstract

Phenolic lipids are a very diversified group of compounds derived from mono and dihydroxyphenols, i.e., phenol, catechol, resorcinol, and hydroquinone. Due to their strong amphiphilic character, these compounds can incorporate into erythrocytes and liposomal membranes. In this review, the antioxidant, antigenotoxic, and cytostatic activities of resorcinolic and other phenolic lipids are described. The ability of these compounds to inhibit bacterial, fungal, protozoan and parasite growth seems to depend on their interaction with proteins and/or on their membrane-disturbing properties.

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Figures

Fig. 1
Fig. 1
The representative structures of selected phenolic lipids. a Anacardic acid (saturated homologue), b cardanol (alkylphenol, saturated homologue), c merulinic acid, d cardol (saturated homologue), e methylcardol (saturated homologue), f climacostol
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