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Review
. 2010 Apr;4(3):148-57.
doi: 10.1016/j.fsigen.2009.09.007. Epub 2009 Oct 2.

Forensic implications of genetic analyses from degraded DNA--a review

Reza Alaeddini  1 , Simon J Walsh, Ali Abbas
Affiliations
Review

Forensic implications of genetic analyses from degraded DNA--a review

Reza Alaeddini et al. Forensic Sci Int Genet. 2010 Apr.

Abstract

Forensic DNA identification techniques are principally based on determination of the size or sequence of desired PCR products. The fragmentation of DNA templates or the structural modifications that can occur during the decomposition process can impact the outcomes of the analytical procedures. This study reviews the pathways involved in cell death and DNA decomposition and the subsequent difficulties these present in DNA analysis of degraded samples.

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