Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010 Mar 9;107(10):E32.
doi: 10.1073/pnas.1000366107.

Release of the mitochondrial endosymbiont helps explain sterile inflammation

Comment

Release of the mitochondrial endosymbiont helps explain sterile inflammation

Seth L Masters et al. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Comment on

References

    1. Iyer SS, et al. Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci USA. 2009;106:20388–20393. - PMC - PubMed
    1. Zimmer C. Origins. On the origin of eukaryotes. Science. 2009;325:666–668. - PubMed
    1. Damås JK, et al. Increased levels of soluble CD40L in African tick bite fever: Possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets. J Immunol. 2006;177:2699–2706. - PubMed
    1. Collins LV, Hajizadeh S, Holme E, Jonsson IM, Tarkowski A. Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses. J Leukoc Biol. 2004;75:995–1000. - PubMed
    1. Crouser ED, et al. Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors. Crit Care Med. 2009;37:2000–2009. - PMC - PubMed

LinkOut - more resources