Isolation of bovine adenovirus type 4 from cattle in Oregon

Abstract

Four isolates of bovine adenovirus type 4 were recovered from Oregon cattle. One isolate was recovered from a 1-week-old calf with pneumoenteritis, and 1 isolate from an 8-month-old bull with fever and respiratory disease. Two isolates were recovered as latent viruses in testicular cell cultures. All 4 isolates of the virus were shown to have certain physical, chemical, biologic, and antigenic characteristics similar to previously described strains of bovine adenovirus type 4. Of 246 adult beef and dairy cattle in Oregon, 51% had serum-viral neutralizing antibodies to the type 4 virus at the 1:8 dilution level.