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Case Reports
. 2010 May;48(5):1978-82.
doi: 10.1128/JCM.01840-09. Epub 2010 Mar 10.

Disseminated Scedosporium/Pseudallescheria infection after double-lung transplantation in patients with cystic fibrosis

Florent Morio  1 , Delphine Horeau-Langlard, Françoise Gay-Andrieu, Jean-Philippe Talarmin, Alain Haloun, Michelle Treilhaud, Philippe Despins, Frédérique Jossic, Laurence Nourry, Isabelle Danner-Boucher, Sabine Pattier, Jean-Philippe Bouchara, Patrice Le Pape, Michel Miegeville
Affiliations
Case Reports

Disseminated Scedosporium/Pseudallescheria infection after double-lung transplantation in patients with cystic fibrosis

Florent Morio et al. J Clin Microbiol. 2010 May.

Abstract

We report a case of disseminated Scedosporium/Pseudallescheria infection due to Pseudallescheria boydii sensu stricto after lung transplantation in a patient with cystic fibrosis. Dissemination occurred under voriconazole. Despite surgery and combination therapy with voriconazole, caspofungin, and terbinafine, the patient died 8 months after transplantation. Previously reported cases are reviewed.

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Figures

FIG. 1.
FIG. 1.
Cerebral magnetic resonance imaging scan showing a large ischemic region located in the right area.
FIG. 2.
FIG. 2.
(A) Direct microscopic examination of the blood culture showing hyphae and conidia (magnification, ×500). (B) Lactophenol cotton blue stain of the fungal culture from blood showing septate hyphae and sessile conidia (magnification, ×1,000). (C) Direct examination of the cardiac vegetation showing several septate hyphae along with conidial formation (magnification, ×400).
See this image and copyright information in PMC

References

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