The pharmacology of immunosuppression

Abstract

Objective: To provide students with a comprehensive, integrated presentation on the pharmacology of immuosuppression.

Design: Course content on the pharmacology of immunosuppression relating to organ transplantation and treatment of autoimmune disorders was presented in integrated sequence modules that included content from pharmacology, medicinal chemistry, and therapeutics. Weekly recitation sessions and active-learning exercises were incorporated to allow students to apply the information they learned to integrated patient cases and stimulate involvement and critical thinking. Fundamental material related to the components and functions of the immune system was presented to students early in curriculum with courses such as biochemistry, pathophysiology, and immunology/microbiology.

Assessment: Comprehensive examinations, in-class quizzes, written case submissions, case discussions, review exercises, and group exercises were used to assess student learning.

Conclusion: Students at South University received a comprehensive and detailed understanding of all aspects relating to immunosuppressive therapy. This was accomplished by integrating instruction on immunosuppressive therapy from various disciplines.

Keywords: autoimmune disease; immune system; immunosuppression; organ transplantation; pharmacology.

Figure 1

Immunosuppressive drugs affecting IL-2.