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Review
. 2010:609:385-400.
doi: 10.1007/978-1-60327-241-4_22.

Protein crystallizability

Pawel Smialowski  1 , Dmitrij Frishman
Affiliations
Review

Protein crystallizability

Pawel Smialowski et al. Methods Mol Biol. 2010.

Abstract

Obtaining well-diffracting crystals remains a major challenge in protein structure research. In this chapter, we review currently available computational methods to estimate the crystallization potential of a protein, to optimize amino acid sequences toward improved crystallization likelihood, and to design optimal crystal screen conditions.

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