An overview of the processes shaping protein evolution
- PMID: 20222353
- PMCID: PMC10365403
- DOI: 10.3184/003685009X12605492662844
An overview of the processes shaping protein evolution
Abstract
From a comparatively small number of protein structural domains a staggering array of structural variants has evolved which has, in turn, facilitated an expanse of functional derivatives. Herein I review the primary mechanisms which have contributed to the vastness of our existing, and expanding, protein repertoires.
Similar articles
-
Proteins: form and function.Bioeng Bugs. 2012 Mar-Apr;3(2):80-5. doi: 10.4161/bbug.18303. Epub 2012 Mar 1. Bioeng Bugs. 2012. PMID: 22095055 Free PMC article. Review.
-
Prediction of protein functions.Methods Mol Biol. 2012;815:15-24. doi: 10.1007/978-1-61779-424-7_2. Methods Mol Biol. 2012. PMID: 22130980 Review.
-
The relationship between domain duplication and recombination.J Mol Biol. 2005 Feb 11;346(1):355-65. doi: 10.1016/j.jmb.2004.11.050. Epub 2004 Dec 23. J Mol Biol. 2005. PMID: 15663950
-
Evolution of the protein repertoire.Science. 2003 Jun 13;300(5626):1701-3. doi: 10.1126/science.1085371. Science. 2003. PMID: 12805536
-
Design of proteins from smaller fragments-learning from evolution.Curr Opin Struct Biol. 2014 Aug;27:56-62. doi: 10.1016/j.sbi.2014.04.007. Epub 2014 May 25. Curr Opin Struct Biol. 2014. PMID: 24865156 Review.
Cited by
-
Under the microscope: From pathogens to probiotics and back.Bioengineered. 2015;6(5):275-82. doi: 10.1080/21655979.2015.1089368. Bioengineered. 2015. PMID: 26339986 Free PMC article. Review.
-
Genes with a large intronic burden show greater evolutionary conservation on the protein level.BMC Evol Biol. 2014 Mar 16;14(1):50. doi: 10.1186/1471-2148-14-50. BMC Evol Biol. 2014. PMID: 24629165 Free PMC article.
-
Detection of selection utilizing molecular phylogenetics: a possible approach.Genetica. 2011 May;139(5):639-48. doi: 10.1007/s10709-011-9560-6. Epub 2011 Mar 13. Genetica. 2011. PMID: 21400220 Free PMC article.
-
Proteins: form and function.Bioeng Bugs. 2012 Mar-Apr;3(2):80-5. doi: 10.4161/bbug.18303. Epub 2012 Mar 1. Bioeng Bugs. 2012. PMID: 22095055 Free PMC article. Review.
-
A beginner's guide to phylogenetics.Microb Ecol. 2013 Jul;66(1):1-4. doi: 10.1007/s00248-013-0236-x. Epub 2013 Apr 28. Microb Ecol. 2013. PMID: 23624570 Review.
References
-
- Chothia C., and Gough J. (2009) Genomic and structural aspects of protein evolution. Biochem. J., 419, 15–28. - PubMed
-
- Brenner S.E., Hubbard T., Murzin A., and Chothia C. (1995) Gene duplications in H. influenzae. Nature, 378, 140. - PubMed
-
- Volff J.N., and Brosius J. (2007) Modern genomes with retro-look: retro-transposed elements, retroposition and the origin of new genes. Genome Dyn., 3, 175–190. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources