doi: 10.1021/ol100350w.
A new powerful strategy for the organocatalytic asymmetric construction of a quaternary carbon stereogenic center
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- PMID: 20222687
- DOI: 10.1021/ol100350w
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A new powerful strategy for the organocatalytic asymmetric construction of a quaternary carbon stereogenic center
Org Lett.
.
Abstract
A new method for chiral diamine-catalyzed Robinson-type annulation was developed to construct cyclohexenone derivatives bearing a quaternary carbon stereogenic center at the 4-position in high enantiomeric excess. This method was successfully applied to the short synthesis of (+)-sporochnol A.
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