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. 2010 Apr 30;28(20):3567-70.
doi: 10.1016/j.vaccine.2010.02.107. Epub 2010 Mar 10.

Mumps vaccine effectiveness in highly immunized populations

Angela Domínguez  1 , Núria Torner, Jesús Castilla, Joan Batalla, Pere Godoy, Marcela Guevara, Dolors Carnicer, Joan Caylà, Cristina Rius, Josep Maria Jansà
Affiliations

Mumps vaccine effectiveness in highly immunized populations

Angela Domínguez et al. Vaccine. .

Abstract

The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.

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