Enhancement of the anti-anabolic response to adenosine 3':5'-cyclic monophosphate during development. The inhibition of hepatic protein synthesis
- PMID: 202263
- PMCID: PMC1183760
- DOI: 10.1042/bj1680271
Enhancement of the anti-anabolic response to adenosine 3':5'-cyclic monophosphate during development. The inhibition of hepatic protein synthesis
Abstract
Cyclic AMP causes an age-dependent inhibition of protein synthesis in rat liver. The onset of inhibition is about 10--12 days after birth. The developmental response to cyclic AMP is associated with a change in the microsomal component of the protein-synthesizing system.