Preliminary estimation of risk factors for admission to intensive care units and for death in patients infected with A(H1N1)2009 influenza virus, France, 2009-2010
- PMID: 20228857
- PMCID: PMC2836028
- DOI: 10.1371/currents.rrn1150
Preliminary estimation of risk factors for admission to intensive care units and for death in patients infected with A(H1N1)2009 influenza virus, France, 2009-2010
Abstract
To estimate the magnitude of the risks associated with age, obesity, pregnancy and diabetes, we compared the prevalence of these conditions reported in hospitalized severe cases to that in the general population, during the 2009-2010 A(H1N1) pandemic flu in France. Pregnancy, obesity, heart failure and diabetes were risk factors for admission into an intensive care unit (OR=5.2 [95%CI 4.0-6.9], 3.8 [3.0-4.9], 3.3 [2.6-4.1] and 2.8 [2.3-3.4], respectively). Only heart failure, obesity, and diabetes were significantly associated with death (OR=6.9 [4.9-9.8], 3.6 [1.9-6.2], and 3.5 [2.5-5.1], respectively). Elderly adults were at lower risk of being admitted into an ICU, but at higher risk of death.
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References
-
- ANZIC Influenza Investigators, Webb SA, Pettilä V, Seppelt I, Bellomo R, Bailey M, Cooper DJ, Cretikos M, Davies AR, Finfer S, Harrigan PW, Hart GK, Howe B, Iredell JR, McArthur C, Mitchell I, Morrison S, Nichol AD, Paterson DL, Peake S, Richards B, Stephens D, Turner A, Yung M. Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med. 2009 Nov 12;361(20):1925-34. - PubMed
-
- Institut de Veille Sanitaire. http://www.invs.sante.fr/surveillance/grippe_dossier/points_h1n1/grippe_...
-
- Institut national de la statistique et des études économiques. http://www.insee.fr/en/default.asp
-
- Kusnik-Joinville O, Weill A, Ricordeau P, Allemand H. Diabète traité en France en 2007 : un taux de prévalence proche de 4% et des disparités géographiques croissantes. BEH 12 novembre 2008 / n° 43.
-
- Étude nationale nutrition santé, 2006. http://www.invs.sante.fr/publications/2007/nutrition_enns/RAPP_INST_ENNS...
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