Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Apr 6;49(16):2929-32.
doi: 10.1002/anie.200907287. Epub 2010 Mar 12.

Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds

Affiliations

Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds

Toshiaki Shimasaki et al. Angew Chem Int Ed Engl. .

Abstract

Catalytic amination: The title reaction demonstrates the use of aryl carboxylates as suitable electrophilic coupling substrates in catalytic amination reactions. N-heterocyclic carbene ligands and NaOtBu promote the amination of aryl pivalates through the cleavage of normally unreactive aryl carbon-oxygen bonds (see scheme; cod=cyclooctadiene).

PubMed Disclaimer

Publication types

LinkOut - more resources