Inhaled corticosteroids and risk of pneumonia: evidence for and against the proposed association
- PMID: 20231237
- DOI: 10.1093/qjmed/hcq023
Inhaled corticosteroids and risk of pneumonia: evidence for and against the proposed association
Abstract
Inhaled corticosteroids (ICS) are commonly used in the treatment of chronic obstructive pulmonary disease. Recent large prospective trials have reported an increased incidence of pneumonia in patients treated with ICS. Despite this, the link between ICS and pneumonia remains controversial. In this review, pro and con arguments for the association between ICS and increased pneumonia risk are discussed, drawing on evidence from experimental and clinical research.
Similar articles
-
Benefits and risks of adjunctive inhaled corticosteroids in chronic obstructive pulmonary disease: a meta-analysis.Clin Ther. 2008 Aug;30(8):1416-25. doi: 10.1016/j.clinthera.2008.08.004. Clin Ther. 2008. PMID: 18803985
-
Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease: a meta-analysis.Arch Intern Med. 2009 Feb 9;169(3):219-29. doi: 10.1001/archinternmed.2008.550. Arch Intern Med. 2009. PMID: 19204211 Review.
-
Inhaled corticosteroids for chronic obstructive pulmonary disease.BMJ. 2012 Oct 25;345:e6843. doi: 10.1136/bmj.e6843. BMJ. 2012. PMID: 23100329 No abstract available.
-
Inhaled corticosteroids in chronic obstructive pulmonary disease: a review.Expert Opin Pharmacother. 2010 Feb;11(3):405-21. doi: 10.1517/14656560903510628. Expert Opin Pharmacother. 2010. PMID: 20102305 Review.
-
Risk of pneumonia with use of inhaled corticosteroids in patients with chronic obstructive pulmonary disease.Indian J Chest Dis Allied Sci. 2010 Oct-Dec;52(4):195-6. Indian J Chest Dis Allied Sci. 2010. PMID: 21302594 No abstract available.
Cited by
-
Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease: How Significant is the Risk of Pneumonia and Should It Impact Use of Inhaled Corticosteroids?Curr Infect Dis Rep. 2011 Jun;13(3):296-301. doi: 10.1007/s11908-011-0176-x. Curr Infect Dis Rep. 2011. PMID: 21394429
-
Experimental rhinovirus infection in COPD: implications for antiviral therapies.Antiviral Res. 2014 Feb;102:95-105. doi: 10.1016/j.antiviral.2013.12.006. Epub 2013 Dec 24. Antiviral Res. 2014. PMID: 24370732 Free PMC article. Review.
-
Glucocorticoids relieve collectin-driven suppression of apoptotic cell uptake in murine alveolar macrophages through downregulation of SIRPα.J Immunol. 2012 Jul 1;189(1):112-9. doi: 10.4049/jimmunol.1200984. Epub 2012 May 21. J Immunol. 2012. PMID: 22615206 Free PMC article.
-
Relationship between the use of inhaled steroids for chronic respiratory diseases and early outcomes in community-acquired pneumonia.PLoS One. 2013 Sep 5;8(9):e73271. doi: 10.1371/journal.pone.0073271. eCollection 2013. PLoS One. 2013. PMID: 24039899 Free PMC article.
-
Appropriate use of inhaled corticosteroids in COPD: the candidates for safe withdrawal.NPJ Prim Care Respir Med. 2016 Sep 29;26:16068. doi: 10.1038/npjpcrm.2016.68. NPJ Prim Care Respir Med. 2016. PMID: 27684954 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical