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. 2010 Mar;7(3):717-21.
doi: 10.1002/cbdv.200900198.

A new long-chain alkene and antituberculosis constituents from the leaves of Pourthiaea lucida

Jih-Jung Chen  1 , Wen-Jiou Lin, Po-Chuen Shieh, Ih-Sheng Chen, Chien-Fang Peng, Ping-Jyun Sung
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A new long-chain alkene and antituberculosis constituents from the leaves of Pourthiaea lucida

Jih-Jung Chen et al. Chem Biodivers. 2010 Mar.

Abstract

A new long-chain alkene, dotriacont-1-ene (1), was isolated from the leaves of Pourthiaea lucida, together with twelve known compounds. The structure of this new compound was determined by NMR and mass-spectrometric analyses. Among the isolated compounds, alpha-tocospiro A (2), alpha-tocopheryl quinone (4), and (E)-phytol (5) exhibited antituberculosis activities (MICs <or=30 microg/ml) against Mycobacterium tuberculosis H(37)Rv in vitro.

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