The role of autophagy as a mechanism of cytotoxicity by the clinically used agent MDA-7/IL-24
- PMID: 20234182
- PMCID: PMC3682463
- DOI: 10.4161/cbt.9.7.11381
The role of autophagy as a mechanism of cytotoxicity by the clinically used agent MDA-7/IL-24
Comment on
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OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins.Cancer Biol Ther. 2010 Apr 1;9(7):526-36. doi: 10.4161/cbt.9.7.11116. Epub 2010 Apr 1. Cancer Biol Ther. 2010. PMID: 20107314 Free PMC article.
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- Fisher PB, Gopalkrishnan RV, Chada S, Ramesh R, Grimm EA, Rosenfeld MR, et al. mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory to the clinic. Cancer Biol Ther. 2003;2:23–37. - PubMed
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- Lebedeva IV, Su ZZ, Chang Y, Kitada S, Reed JC, Fisher PB. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells. Oncogene. 2002;21:708–18. - PubMed
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