Nitrous oxide inhalation among adolescents: prevalence, correlates, and co-occurrence with volatile solvent inhalation
- PMID: 20235440
- PMCID: PMC2921531
- DOI: 10.1080/02791072.2009.10399771
Nitrous oxide inhalation among adolescents: prevalence, correlates, and co-occurrence with volatile solvent inhalation
Abstract
Few studies have examined the prevalence of nitrous oxide (NO) inhalation or co-occurrence of NO and volatile solvent (VS) use in adolescents. Study aims were to (1) describe the independent and conjoint prevalence of NO and VS use in incarcerated youth, (2) compare adolescent users of both NO and VS inhalants (NO+VS) to users of NO-only, VS-only, and nonusers of NO and VS (NO/VNS nonusers) with regard to demographic, psychological, and behavioral characteristics, and (3) conduct logistic regression analyses identifying correlates of NO use. Residents (N = 723) of Missouri Division of Youth Services were assessed with standardized psychosocial measures. Participants averaged 15.5 (SD = 1.2) years of age, were ethnically diverse and predominantly male. Lifetime prevalence of NO use was 15.8%. NO+VS users evidenced greater impairments compared to NO+VS nonusers. VS-only users evidenced impairments that were similar in kind but at lower prevalences compared to those displayed by NO+VS users, whereas NO-only youth had profiles that were similar to those of NO/VS nonusers. Psychiatric disorders, polydrug use, and temperamental fearlessness were correlates of NO use. NO+VS users were at high risk for behavioral and emotional problems. Screening and interventions for NO and VS inhalant use should be implemented in juvenile justice facilities.
Similar articles
-
Inhalant use among incarcerated adolescents in the United States: prevalence, characteristics, and correlates of use.Drug Alcohol Depend. 2008 Mar 1;93(3):197-209. doi: 10.1016/j.drugalcdep.2007.08.023. Epub 2007 Nov 5. Drug Alcohol Depend. 2008. PMID: 17983710
-
Adolescent inhalant use, abuse and dependence.Addiction. 2009 Jul;104(7):1185-92. doi: 10.1111/j.1360-0443.2009.02557.x. Epub 2009 Apr 29. Addiction. 2009. PMID: 19426292
-
Endemic asthma inhaler abuse among antisocial adolescents.Drug Alcohol Depend. 2008 Jul 1;96(1-2):22-9. doi: 10.1016/j.drugalcdep.2008.01.022. Epub 2008 Mar 14. Drug Alcohol Depend. 2008. PMID: 18343052
-
Clinical review of inhalants.Am J Addict. 2001 Winter;10(1):79-94. doi: 10.1080/105504901750160529. Am J Addict. 2001. PMID: 11268830 Review.
-
Does vitamin B12 deficiency explain psychiatric symptoms in recreational nitrous oxide users? A narrative review.Clin Toxicol (Phila). 2021 Nov;59(11):947-955. doi: 10.1080/15563650.2021.1938107. Epub 2021 Aug 4. Clin Toxicol (Phila). 2021. PMID: 34348072 Review.
Cited by
-
Megaloblastic hematopoiesis in a 20 year old pregnant female.Am J Case Rep. 2013;14:10-2. doi: 10.12659/AJCR.883734. Epub 2013 Jan 11. Am J Case Rep. 2013. PMID: 23569553 Free PMC article.
-
The Clinical Presentations of Nitrous Oxide Users in an Emergency Department.Toxics. 2022 Feb 26;10(3):112. doi: 10.3390/toxics10030112. Toxics. 2022. PMID: 35324737 Free PMC article.
-
Electrophysiologic Characteristics of Nitrous-Oxide-Associated Peripheral Neuropathy: A Retrospective Study of 76 Patients.J Clin Neurol. 2023 Jan;19(1):44-51. doi: 10.3988/jcn.2023.19.1.44. J Clin Neurol. 2023. PMID: 36606645 Free PMC article.
-
[Clinical features of long segmental myelopathy caused by nitrous oxide].Beijing Da Xue Xue Bao Yi Xue Ban. 2019 Apr 18;51(2):288-292. doi: 10.19723/j.issn.1671-167X.2019.02.017. Beijing Da Xue Xue Bao Yi Xue Ban. 2019. PMID: 30996370 Free PMC article. Chinese.
-
Volatile substance misuse : clinical considerations, neuropsychopharmacology and potential role of pharmacotherapy in management.CNS Drugs. 2012 Nov;26(11):927-35. doi: 10.1007/s40263-012-0001-6. CNS Drugs. 2012. PMID: 23018545 Review.
References
-
- American Psychiatric Association (APA) Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revision. Washington, D.C.: APA; 2000.
-
- Baker TB, Piper ME, McCarthy DE, Majeskie MR, Fiore MC. Addiction motivation reformulated: An affective processing model of negative reinforcement. Psychological Review. 2004;111(1):33–51. - PubMed
-
- Beckman NJ, Zacny JP, Walker DJ. Within-subject comparison of the subjective and psychomotor effects of a gaseous anesthetic and two volatile anesthetics in healthy volunteers. Drug and Alcohol Dependence. 2006;81(1):89–95. - PubMed
-
- Blanton A. Nitrous oxide abuse: Dentistry's unique addiction. Journal of the Tennessee Dental Association. 2006;86(4):30–31. - PubMed
-
- Brodsky L, Zuniga J. Nitrous oxide: A psychotogenic agent. Comprehensive Psychiatry. 1975;16(2):185–88. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical