Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Jan 28;11(1):203.
doi: 10.1186/gb-2010-11-1-203.

Looking for signatures of sex-specific demography and local adaptation on the X chromosome

Evelyne Heyer  1 , Laure Segurel
Affiliations
Review

Looking for signatures of sex-specific demography and local adaptation on the X chromosome

Evelyne Heyer et al. Genome Biol. .

Abstract

A population study comparing X-linked variation with that of the autosomes reveals that social organization has a clear impact on X chromosome genetic diversity and that the X chromosome shows a signature of local adaptation.

PubMed Disclaimer

References

    1. Casto AM, Li JZ, Absher D, Myers R, Ramachandran S, Feldman M. Characterization of X-linked SNP genotyping variation in globally-distributed human populations. Genome Biol. 2010;11:R10. - PMC - PubMed
    1. Hamilton G, Stoneking M, Excoffier L. Molecular analysis reveals tighter social regulation of immigration in patrilocal populations than in matrilocal populations. Proc Natl Acad Sci USA. 2005;102:7476–7480. doi: 10.1073/pnas.0409253102. - DOI - PMC - PubMed
    1. Oota H, Settheetham-Ishida W, Tiwawech D, Ishida T, Stoneking M. Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence. Nat Genet. 2001;29:20–21. doi: 10.1038/ng711. - DOI - PubMed
    1. Chaix R, Quintana-Murci L, Hegay T, Hammer MF, Mobasher Z, Austerlitz F, Heyer E. From social to genetic structures in central Asia. Curr Biol. 2007;17:43–48. doi: 10.1016/j.cub.2006.10.058. - DOI - PubMed
    1. Ramachandran S, Rosenberg NA, Zhivotovsky LA, Feldman MW. Robustness of the inference of human population structure: a comparison of X-chromosomal and autosomal microsatellites. Hum Genomics. 2004;1:87–97. - PMC - PubMed

LinkOut - more resources