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Review
. 2010;14(2):215.
doi: 10.1186/cc8856. Epub 2010 Mar 9.

Cerebral perfusion in sepsis

Affiliations
Review

Cerebral perfusion in sepsis

Christoph S Burkhart et al. Crit Care. 2010.

Abstract

This article is one of ten reviews selected from the Yearbook of Intensive Care and Emergency Medicine 2010 (Springer Verlag) and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/yearbook. Further information about the Yearbook of Intensive Care and Emergency Medicine is available from http://www.springer.com/series/2855

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Figures

Figure 1
Figure 1
Synopsis of documented and hypothetical factors influencing cerebral perfusion in sepsis. Some of the factors (e.g., nitric oxide [NO]) influence cerebral perfusion at different levels of the brain circulation. It could be speculated that the effect of vasopressors may be unpredictable depending on the degree of blood-brain barrier dysfunction. MAP: mean arterial pressure; CPP: cerebral perfusion pressure; ICP: intracranial pressure.

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