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Comment
. 2010;14(1):122.
doi: 10.1186/cc8228. Epub 2010 Feb 16.

Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?

Greet Van den Berghe
Comment

Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?

Greet Van den Berghe. Crit Care. 2010.

Abstract

A small study in patients with severe sepsis suggested that insulin infused to normalize blood glucose levels increased forearm flow. This clinical observation supports the effect of insulin on the endothelium, as previously shown by in vitro studies and by in vivo animal models of critical illness, but the clinical consequences remain unclear.

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