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Comment

. 2010 Mar 15;9(6):1025.

doi: 10.4161/cc.9.6.11155. Epub 2010 Mar 15.

Targeting Chk1 in the replicative stress response

Yun Dai¹, Steven Grant

Affiliations

PMID: 20237419
PMCID: PMC3713111
DOI: 10.4161/cc.9.6.11155

Comment

Targeting Chk1 in the replicative stress response

Yun Dai et al. Cell Cycle. 2010.

. 2010 Mar 15;9(6):1025.

doi: 10.4161/cc.9.6.11155. Epub 2010 Mar 15.

Authors

Yun Dai¹, Steven Grant

Affiliation

¹ Virginia Commonwealth University, Richmond, VA, USA.

PMID: 20237419
PMCID: PMC3713111
DOI: 10.4161/cc.9.6.11155

No abstract available

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Comment on

Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase.
McNeely S, Conti C, Sheikh T, Patel H, Zabludoff S, Pommier Y, Schwartz G, Tse A. McNeely S, et al. Cell Cycle. 2010 Mar 1;9(5):995-1004. doi: 10.4161/cc.9.5.10935. Epub 2010 Mar 14. Cell Cycle. 2010. PMID: 20160494

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References

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1. Shao RG, Cao CX, Shimizu T, O’Connor PM, Kohn KW, Pommier Y. Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function. Cancer Res. 1997;57:4029–35. - PubMed
1. Sampath D, Cortes J, Estrov Z, Du M, Shi Z, Andreeff M, et al. Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. Blood. 2006;107:2517–24. doi: 10.1182/blood-2005-08-3351. - DOI - PMC - PubMed

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