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Comment
. 2010 Mar 15;9(6):1025.
doi: 10.4161/cc.9.6.11155. Epub 2010 Mar 15.

Targeting Chk1 in the replicative stress response

Yun Dai  1 , Steven Grant
Affiliations
Comment

Targeting Chk1 in the replicative stress response

Yun Dai et al. Cell Cycle. .
No abstract available

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References

    1. Dai Y, Grant S. New insights into checkpoint kinase 1 in the DNA damage response signaling network. Clin Cancer Res. 2010;16:376–83. doi: 10.1158/1078-0432.CCR-09-1029. - DOI - PMC - PubMed
    1. Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature. 2004;432:316–23. doi: 10.1038/nature03097. - DOI - PubMed
    1. Sørensen CS, Hansen LT, Dziegielewski J, Syljuåsen RG, Lundin C, Bartek J, et al. The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat Cell Biol. 2005;7:195–201. doi: 10.1038/ncb1212. - DOI - PubMed
    1. Shao RG, Cao CX, Shimizu T, O’Connor PM, Kohn KW, Pommier Y. Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function. Cancer Res. 1997;57:4029–35. - PubMed
    1. Sampath D, Cortes J, Estrov Z, Du M, Shi Z, Andreeff M, et al. Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. Blood. 2006;107:2517–24. doi: 10.1182/blood-2005-08-3351. - DOI - PMC - PubMed

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