doi: 10.1039/b925483h.
Epub 2010 Feb 5.
Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli
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- PMID: 20237660
- DOI: 10.1039/b925483h
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Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli
Org Biomol Chem.
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Abstract
Biosynthetic studies with (13)C-labelled acetates and methionine revealed that the infamous, food-related toxin bongkrekic acid from Burkholderia gladioli is a polyketide with acetate-derived beta-branches and a carboxylate terminus derived from the methyl group of an acetate.
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